Fire crews have been called to Guildhall Road tonight where they are attending an ongoing incident.
Eyewitness Gareth Eales has reported a "horrific smell of smoke" at the top of Guildhall Road and three fire engines are now in attendance. There are unconfirmed reports that the fire may be in the museum.
Guildhall Road has been taped off to oncoming motorists and traffic delays have been reported on St Giles Street.
Bartender at The Mailcoach Eaymen Jones said: "They have taped off the street and coned off the road, Derngate is still open.
"As soon as you step outside of the pub all you can smell is smoke"
Updates to follow.